#38 – Chronic Inflammatory Response Syndrome with Judy Cho – The Mikhaila Peterson Podcast
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QUOTES:
My diet and my recommendations were so wrong, and I'm such an inquisitive person that I needed to figure out why. So, when I was on medical disability for my mental illness and breakdown I just started researching all this stuff about food, and nutrition, and biochemistry, and I got mad. So, I quit my job, I went back to nutritional therapy school, and then I just started advocating. I learned so much about how to make presentations for CEOs, and making a case, and that's what I now do for a carnivore diet, and it's not just about this is dogma, a Bro Science or bro diet, I don't believe in that, it's just, I want people to heal and if I need to prove the science to you so that you can heal using this diet then by all means I will do that
Once I became asymptomatic, I was slowly able to reintroduce foods. There's some sort of gut healing that takes place
I still have crazy inflammatory responses now, they're not like before diet. When I first started, they were so bad that it would hit me for a month and now it's not like that
What we found over the years is that carnivore doesn't fix everything
Over the years, every single one of my client patients has challenged me to think otherwise, so I used to think liver was the best thing to add if you're a nutrient deficient or you’re anorexic, it's not always the case. Then I realized that carnivore doesn't fix everyone, it does a lot of improvement because it's essentially reducing your overall inflammation, especially when it comes to foods that your body is intolerant to
When you have eaten all meat from six months to a year, and the needle has not moved enough to optimal health healing, if you choose to add other things you can't add it back, that to me means that carnivore is becoming a Band-Aid. It's optimal diet but still there's something else, and that's when I think people should start looking at environmental toxins and one of them is related to CIRS
CIRS is a chronic inflammatory response syndrome. 20% of the population may be affected by it. We have two sides to our immune system. One is the innate immune side, and the other is the adaptive. Just to make it super simple, the innate is the initial immune response, the more basic immune function. But when the “foreigner” is a lot more complicated, the innate side then release antigens or communications to the adaptive side, saying “hey, T-cells, B-cells, memory cells, I need you to come in and remove this toxin because we can't handle it.” The way that it does that is by releasing cytokines to communicate, and then normally the adaptive side will come in and remove the toxin. But 20% to 25% of the population cannot do the trade-off, so what ends up happening is the innate side gets super inflamed and is saying “hey, there's this ‘foreigner’ in our system and I need it to be removed” and the adaptive side has no idea and will never know about it
We get exposed to these biotoxins, it could be water damaged buildings, it could be a recluse spider bite, it could be Lyme disease, lots of things that are natural toxins in our environment, and it gets into our system, and the 20% of the population does not recognize to remove it
What we're trying to do over time with CIRS is that we're trying to call that immune response, you can take some binders [substances that hold other materials together], and if the binder is specific, it will actually pull those toxins that are in your system that the other side of your immune system was not able to remove, and then you can start to find healing
Immune system is not able to turn off that level of inflammation because the other side is not able to recognize it and shut it off
Over time, if your toxin bucket load gets filled, and now it starts overflowing, that's when the symptomology becomes really present, and you will start feeling what they call a “multi-system multi-symptom” – it affects many of your systems in your body and then it has multiple symptoms
I just saw a statistic where if you get a second diagnosis, 80% is usually different, so how do you know that the diagnosis you got is correct?
In 2008, the U.S. GAO accepted that CIRS is an illness, that mold in your homes from water damage buildings can make you sick, so it is accepted, the community at large or the medical industry at large accepts mold as a true illness. But there are so many mold protocols online and it's not getting to the root cause, the root cause is the chronic inflammation
When we get sick from this illness, we produce a lot of cortisol, and that affects our brain. Initially our brain has an excess of cortisol in the hippocampus, then it affects our hypothalamus, and then it affects our pituitary. And at first, that innate immune system is trying to tell the adaptive side “There’s a fire, we need to resolve this” and cortisol is obviously that stress response, but nothing happens. And over time the brain says “we need to shut down,” we have too much saturation of cortisol in the hippocampus. And when that shutdown happens then the other parts of the brain start also saying “we need to shut down to protect this body from dying.” And when that shutdown happens, that's when that master hormone – the melanocyte stimulating hormones [ MSH ] – reduces. And it's when that reduction happens that every downstream symptomology starts to occur – that's when our hormones get messed up, the chronic pain, lack of sleep, the electrolyte issues…
When we don't eat or consume a lot of glucose, we have less water retention. So, if we are naturally imbalanced in our electrolytes, no matter how much sodium or electrolytes we consume, we're not balancing. If that's an issue, carbs will mask it, but it's not resolving it. For example, when you have the low MSH, it affects your antidiuretic hormone [ ADH ], and that ADH is what helps you to hold on to water. So, there's a lot of carnivores who are constantly thirsty, constantly drinking, but the ADH hormone is low, so they just keep peeing it out, so they never feel hydrated
A big component of CIRS is mental illness. It's a huge component. A lot of the markers affect your blood brain barrier and cause it to be permeable. A lot of people have been diagnosed with bipolar, they will go to their doctors, and then they'll do all the blood work on the adaptive side, which is not the side that this is affecting, and the doctor says “your CRP looks good, your insulin is good,” but because they're on a carnivore diet everything's good. And then the doctor says “I think it's in your head” and they recommend them to a psychiatrist, and they get them on meds, because they are believing or feeling these fake symptoms. And as we test for CIRS, we realize that actually there are toxins that are getting into your brain, because it's breached from the blood-brain barrier, because of the certain markers that are inflamed
Many of my clients, their immune system looks wonderful, all the markers look great, but then when we test the innate side and there's so much inflammation
If you want to eat other foods, you should be able to, that's the goal. The goal is to root cause and being able to tolerate a lot of other foods for you
There is a point where carnivore only works to a certain point, and then you have to look further
One patient was never able to consume dairy, she had histamine reactions for anything, she only ate grass-fed, she did a lion diet, she improved a lot but then her symptoms would eventually kind of come back, depending on the environment. And once she started working with me, we did gut supports, again it helped a little bit but not enough, until we found CIRS
- I had mold exposure when I was young, but I’ve been pretty careful about my environment. Wouldn't your body after five years, wouldn't those toxins just go away naturally?
- If you are part of that 20% genetic susceptibility, it won't go away. It doesn't know how to remove it, because the adaptive side. Most of the mold that we get sick from is not the water damage, the one with that the active mildewy smell. It's when spores or mold dries up, and then it breaks into fragments, and I think one spore breaks into thousands of fragments, and it's those really small bits that can breach the blood-brain barrier, and those are the ones that actually make us sicker
Your immune system works together so every person will manifest the symptoms differently
You could just get tested. That's the easiest way to know if your inflammatory responses system on the innate side heightened. And then what we can do is to just reduce every single inflammatory marker and that's the goal
We all have a toxin bucket which as you're growing up it'll keep loading, and loading, and eventually the bucket will overflow, and once it overflows that's when you feel the symptomology. So when you're young you may not feel as much, you might have little headaches, the tiredness because of the genetic susceptibility, but over time if this bucket is fully full, you will start feeling sick
Honey, a lot of times, is not being regulated. So sometimes they might add more color to make it look more ambery. It's just not regulated, you don't know if you're getting a little bit of high fructose corn syrup in it
In my practice, if someone is having issues with thyroid markers, I will always recommend them to take a little bit of iodine
I always measure a few markers for health: it's your sleep, your mood, your energies, your stool, and your hormones
The best way is listening and honoring your body's reactions. After three to five days of using the same food and then increasing its dose, if you are feeling fine then that food is probably safe for you. And then you keep doing that with every food you want to reintroduce, and if you have a bad reaction, you want to go back to the baseline. By eating your baseline foods, you wait for that symptomology to go down back, and then again start to test a different food
You can eat one thing, you can get your inflammation levels down, track your food, introduce new one by one, and see what happens
Your body's mechanisms and symptoms are the strongest way to know if something is working or if it's not
If your body makes sense, it never has symptoms. And if it does have symptoms, it's telling you that something's off. So, when people supplement hormones, and they say “I found that I'm low in estrogen so I should start supplementing estrogen” or when they start supplementing with progesterone, you have to find out why you're low, because your body will do the best it can with what it has
It's not that the diet's wrong, it's just that you might have something else additional to food
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